Ubiquinol is also known as QH and is the bioactive variant of the “cell fuel” coenzyme Q10. Thanks to a special process, it is available in a stable form.

The special cell fuel, which supports the body's energy production, cell structure and the fight against free radicals, can be absorbed by the organism much better than coenzyme Q10 and can also be stored for longer.

In 2005, scientists at Kaneka™ succeeded in producing QH safely and stably after a long time. The bioactive, directly available form of Q10 was difficult to isolate until then, as QH quickly decomposes (oxidizes) in air. Thanks to an innovative process by the quality manufacturer Kaneka™, QH can be introduced into soft gel capsules. The QH dissolved in oil is best absorbed and utilized by the body.

Kaneka is still the only manufacturer in the world that guarantees a solid and controlled quality of QH. Small tip: Make sure you look for the quality mark KanekaQH™. In the Medicom shop you can also find the high-quality Ubiquinol QH from Kaneka as QH Mono 50 mg .

QH is involved in the body's own energy conversion in every cell and neutralizes free radicals with its antioxidant effects. QH is particularly suitable for older people, as enzyme activity is often reduced in this group. QH is needed above all in organs with high energy requirements, such as the heart. People with cardiovascular problems can also benefit from an additional supply of QH. The same applies to patients who take cholesterol-lowering drugs, as these also block the body's own QH production. Finally, a QH supplement is also recommended for increased oxidative stress, which is caused by vigorous physical activity and competitive sports, but also by an unbalanced diet, everyday stress, alcohol and cigarettes.

Bioactive Q10 has been and is being intensively researched in science. The studies range from Promoting heart health, preventing Q10/QH deficiency when taking cholesterol-lowering drugs (statins) and improving mental and physical performance. Ubiquinol may also be relevant for postmenopause and the aging process, according to studies. (Click here and scroll down for studies on heart health, postmenopause and aging)

Below you will find further selected studies on bioactive Q10, QH (ubiquinol) and its positive effects on health.

Not only does the body's own Q10 production decline from the age of 40, the ability to convert Q10 to QH also steadily decreases with advancing age. This is why experts recommend an additional QH dosage from the age of 60. Aging is primarily a decline in physical functions. Studies have shown that oxidative stress and mitochondrial dysfunction are two key factors in the aging process. (1) QH delays the aging process through reactive oxygen species (free radicals) (2) and slows down cell aging by maintaining mitochondrial function. (3) In a study with healthy seniors (73 to 87 years old) who took 100 mg of QH daily for six months, it was shown that they had increased "vitality" and "mental health". (4) It has also been shown in younger people that taking ubiquinol increases the QH concentration in the brain because the active ingredient can pass through the blood-brain barrier. This improves the brain's mitochondrial metabolism. (5) Reduced ubiquinol levels increase the susceptibility to dementia. (6)

(1) Hang Cui et al., J. of Signal Transduction, 2012
(2) Jia Huo et al. Oxide. Med Cell Longev. 2018
(3) Niu et al.Aging 2020
(4) Deguchi et al. J Clin Therap Med, 223-238, 2008 v University of Tsukuba
(5) Mitsui et al. Cerebelum 2017
(6) Yamagishi et al. Atherosclerosis 2014

Studies increasingly indicate that there is a close connection between an undersupply of ubiquinol and malfunctions of the cardiovascular system.(7) It has been shown that the QH level correlates with cardiac function.(8) It has also been shown that taking ubiquinol in the case of an undersupply leads to an improvement in the diastolic function of the left ventricle.(9) A sufficiently high QH level can thus prevent diastolic heart failure, which is favored by high blood pressure and advanced age.

(7) Zozina et al., Current Cardiology Reviews, 2018, 14, 164-174
(8) Chen, F.-L. et al. Nutrients 2018, 10, 1697
(9) A. Bates et al., 2014

Ubiquinol also plays a role in the defense against pathogens. Studies have shown that a sufficiently high QH level significantly inhibits the spread of flu viruses in the human organism.(10) As early as 1993, a study showed that taking ubiquinol improves the immune response by increasing the amount of T4 and T8 lymphocytes.(11)

(10) Hayashi et al., 2012
(11) Folkers et al., 1993

There are many types of stress for the organism. These include the regular intake of toxins such as nicotine and alcohol, an unbalanced diet, chronic illnesses, psychological stress, but also hard physical work and competitive sports. Taking ubiquinol can also be helpful here. One study shows that taking QH reduces the physical symptoms of work-related stress. (13) Another study found that taking 150 mg of QH daily over a period of eight weeks can alleviate exhaustion and depressive symptoms and improve sleep quality. (14) The heart and muscles also need larger amounts of QH when performing at a higher level. German Olympic athletes who took 300 mg of ubiquinol daily as a dietary supplement for six weeks were able to improve their physical performance. (15) A fitness coach for the French professional ice hockey team Lyon also sees a positive effect of ubiquinol on the mental strength of the players. (16)

(13) Y.Kawaharada et al, 2013
(14) Fukuda et al., 2012
(15) Alf D. et al., Journal of the International Society of Sports Nutrition, 2013
(16) René Mème, Physical training Coach 2014 Lyons Ice Hockey Champion French league