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What to look for when buying collagen

Author: Ana Gómez 

published on 2026-01-14

Many women start paying more attention to collagen in their mid-thirties. The reason is simple: collagen is one of the most important structural proteins in the body and plays a central role in the skin, connective tissue, and nails, among other things.

 

As we age, the body's own collagen structure changes. This natural process can manifest itself, for example, in decreasing skin elasticity, slower skin regeneration, or changes in hair and nails.

 

That's why many women turn to collagen supplements. The expectation is understandable: if the body produces less collagen, it makes sense to supplement this building block through diet. Unfortunately, many have a frustrating experience: despite regular intake, little seems to change.

 

One possible reason for this is that collagen products on the market differ greatly – both in the structure of the peptides they contain and in the quality of the raw materials used. Therefore, anyone who wants to take collagen should pay particular attention to three criteria.

1. The structure of collagen peptides

Not all collagen is created equal. The form it takes is crucial.

 

Many products contain ordinary collagen hydrolysate. These are protein fragments from collagen that have been broken down, but their size and composition can vary greatly.

 

Modern collagen supplements, however, use so-called bioactive collagen peptides. These are produced through a targeted enzymatic manufacturing process. In this process, collagen molecules are broken down to create peptides with a very small and uniform molecular size.

 

"Defined structure" means that these peptides have a clearly determined length and composition. This allows for better investigation and standardization of their absorption in the body.

2. Scientifically Researched Raw Materials

Another important criterion is the collagen raw material used.

 

Numerous products use generic collagen hydrolysate, sourced from various manufacturers. For these raw materials, it is often not precisely documented what peptide sizes or structures are present.

 

Some manufacturers, instead, rely on so-called branded raw materials. These are produced under controlled manufacturing conditions and have a standardized peptide composition.

 

These raw materials are sometimes also investigated in studies to better understand how the contained peptides behave in the body. Their effect can be proven in studies. An example of this is bioactive collagen peptides such as VERISOL® B.

3. Quality instead of the highest possible dosage

A common misconception is that large amounts of collagen are automatically better. That's why many manufacturers recommend daily amounts of 10 to 15 grams.

 

However, with high-quality bioactive peptides, such an amount is often not necessary. What is crucial is not so much the total amount, but rather the structure and bioavailability of the peptides.

 

Products with specially developed collagen peptides, such as the aforementioned branded raw material VERISOL® B, therefore require significantly lower daily dosages.

In comparison: How to recognize high-quality collagen

Many consumers compare collagen products primarily based on price or gram count. In reality, however, other criteria are crucial.

Typical standard collagen:

  • large or inconsistent peptide structures
  • often very high daily dosages of 10 to 15 g
  • raw materials without clearly defined peptide composition

High-quality collagen peptides:

  • small, standardized peptide structures
  • scientifically studied branded raw materials
  • significantly lower daily dosages possible

Conclusion: When it comes to collagen, quality is key.

Therefore, those who want to take collagen should not only pay attention to the advertised grammage. More important are the structure of the peptides, scientifically researched raw materials, and a sensible dosage.

 

An example of such specially developed collagen peptides are the "VERISOL® B" peptides, which are used in some modern collagen supplements. They have a defined structure and are effective even in small daily amounts.

 

A product that was developed precisely according to these criteria is Medicom's Collagen Peptides. They combine high-quality raw materials of the right collagen types and allow for small serving sizes.

 

The tasteless powder contains bioactive collagen peptides (VERISOL® B) and is taken daily in a small portion of 2.5 grams. The powder can be easily stirred into coffee, tea, or smoothies and is free of additives.

Collagen Peptides from Medicom

If you don't judge collagen by grams but by biological efficacy, Medicom's collagen peptides are worth a look.

 

Advantages at a glance:

  • Bioactive collagen peptides (VERISOL® B)
  • Only 2.5 grams daily
  • Neutral taste and easily soluble
  • Free from additives

Despite its high quality, a daily dose costs less than 50 cents. And with the 90-day money-back guarantee, you can try the product risk-free.


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What do collagen peptides really do?

Collagen powder provides the body with the building blocks it needs to regenerate skin, hair, nails, joints, and connective tissue.  

The hydrolyzed collagen in peptide form is particularly well absorbed and acts as a signaling molecule in the body: It activates fibroblasts in the skin, which then produce more of the body's own collagen. This strengthens the skin structure, can reduce wrinkles, and improves moisture. Prerequisite: It must be a collagen with clinically proven effectiveness - such as VERISOL® B.  

In addition, tendons, ligaments, and cartilage also benefit, which makes collagen powder particularly interesting for active athletes and older people.  

What exactly is in collagen peptides – and why is it important for skin & hair?

Collagen peptides consist of short chains of specific amino acids which, when ingested, specifically activate processes of skin regeneration in the body – especially the body's own production of collagen, elastin, and hyaluronic acid.

The most important amino acids in collagen are glycine, proline, and hydroxyproline. They play a central role in the structure, elasticity, and firmness of the skin – as they form the framework of the collagen fibers in the connective tissue.

However, with increasing age, the body's own production of collagen decreases. The result: The skin loses elasticity, becomes drier, and shows initial lines and wrinkles. This is exactly where hydrolyzed collagen peptides come in: Collagen is broken down with water and enzymes, making it particularly small (approx. 2,000 Daltons). The body can absorb them more easily and utilize them better.

VERISOL® B collagen peptides specifically deliver the bioactive collagen building blocks that your skin needs to stimulate its own collagen synthesis again. Studies show: The skin becomes more elastic, smoother, and visibly fresher – from the inside out.

In short: The ingredients in collagen peptides provide your body with exactly what it needs to strengthen its natural skin structure and effectively slow down the aging process.

Does collagen help for shiny, strong hair? 

Yes, collagen can also contribute to the care of hair and nails – provided it is bioactive collagen peptides with proven efficacy. The amino acids it contains, especially glycine, proline, and hydroxyproline, support the formation of keratin – the main component of hair and nails.
 

For hair, studies show: Bioactive collagen peptides can promote hair growth, improve hair density, and shorten the resting phase of hair follicles – a potential benefit, for example, in cases of hormonal changes or age-related hair loss¹.
 

For nails, it has been demonstrated: Taking 2.5 g of collagen peptides daily for 24 weeks reduced nail brittleness by 42%, improved nail growth, and increased nail strength².
 

Crucially, here too, are: quality, small peptide size, and daily application for at least 3 months.

 

Sources:

¹ Oesser S., 2020. The oral intake of specific bioactive collagen peptides has a positive effect on hair thickness. Nutrafoods.

² Hexsel et al., 2017. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. J Cosmet Dermatol.

Does collagen powder help against wrinkles?

Yes, high-quality collagen powder can visibly reduce wrinkles – provided it contains bioactive collagen peptides with clinically proven efficacy. Studies with the branded ingredient VERISOL® B show: skin elasticity improves and wrinkle depth reduces – especially around the eyes and cheeks. (1) 

 

The reason: collagen peptides don't just act as building blocks – they function as signaling agents for skin cells. They stimulate fibroblasts in the dermis (the middle layer of the skin) to produce more endogenous collagen and elastin. This strengthens the skin structure from within and allows it to measurably regenerate. 

 

It is crucial that you choose a product with a small peptide size (approx. 2,000 Daltons) and proven bioavailability. Why? Only then can the peptides enter the bloodstream, act actively, and achieve long-term results. 

 

For visible results, you need one thing above all: quality and daily consistency. Ideally, take the collagen for at least 3 months – then your skin will show you the results. 

(1) E. Proksch et. al., Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis, in Skin Pharmacol Physiol (2014)

Why is the molecular size – about 2,000 Daltons – so important for collagen?

For collagen to work in the body, it must first be absorbed. Large molecules from conventional collagen powder are often too difficult to digest – the body cannot properly utilize them and simply excretes them again. 

 

Collagen peptides with a small molecular size (for example, approx. 2,000 Daltons), on the other hand, are broken down in such a way that they are particularly well absorbed and utilized by the body. After ingestion, they reach the bloodstream more quickly and stimulate skin cells to produce more of their own collagen. 

 

This is the decisive advantage: they not only act as a building block but also specifically activate the natural skin renewal from within – exactly where wrinkles form. 

 

Good to know: Dalton is a unit of measurement for molecular size – the smaller, the better the absorption in the body. 

What do Collagen Type I, Type II, and Type III stand for?

The different types of collagen (Type I, II, and III) perform various functions in the body. Type I and Type III are primarily found in skin, connective tissue, tendons, bones, and blood vessels – they are responsible for elasticity, strength, and structure. Type II, on the other hand, is mainly found in articular cartilage, where it provides elasticity and cushioning.

 

In a collagen hydrolysate – i.e., hydrolyzed collagen powder, such as that contained in the Medicom product Collagen Peptides – the long collagen chains are enzymatically broken down into shorter peptides. These bioavailable collagen peptides are more easily absorbed and utilized by the body. These peptides are no longer recognized by the body as "Type I, II, or III" but rather as amino acid building blocks that are used wherever the body needs them – including in joints, blood vessels, and connective tissue.

 

Therefore, a high-quality collagen hydrolysate from Type I and III can support the entire collagen metabolism – including the structures that depend on Type II. The crucial factor is not the type of collagen in the product, but the bioavailability and peptide structure of the amino acids it contains.
 

Can collagen be taken permanently and how much should I take daily?

Yes – and it is even recommended. Collagen is a natural protein that is well tolerated by the body. Since the body's own collagen production decreases from about 30 years of age, long-term supplementation is useful to counteract the natural degradation. There are no known side effects with long-term intake of high-quality, hydrolyzed collagen. 

 

The only important thing is to choose a product that is pure, well-tolerated and scientifically proven. Our product meets these criteria – for daily use without compromise. 

Collagen is not just collagen. When taking collagen powder, look for collagen peptides from collagen hydrolysate with a molecular size of 2,000 Daltons. For this form of collagen, a dose of 2.5 g per day is recommended.

Why do men and women like to use collagen?

As men age – just like women – their bodies' natural collagen production decreases. This affects not only skin and connective tissue but also joints, tendons, and blood vessels. Collagen peptides of type I & III can specifically help here: They promote the structural strength of tissues, improve regeneration after exercise, and – thanks to the amino acid L-Arginine, which is naturally present in collagen – contribute to vascular health and blood circulation.

*Sources:

J Calleja-Agius, Y Muscat-Baron, M P Brincat, NCBI, "Skin ageing", at https://pubmed.ncbi.nlm.nih.gov/17540135/

E Proksch, D Segger, J Degwert, M Schunck, V Zague, S Oesser, NCBI, "Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study", at: https://pubmed.ncbi.nlm.nih.gov/23949208/

E Proksch, M Schunck, V Zague, D Segger, J Degwert, S Oesser, NCBI, "Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis", at: https://pubmed.ncbi.nlm.nih.gov/24401291/

Michael Schunck, Vivian Zague, Steffen Oesser, Ehrhardt Proksch, NCBI, "Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology, at: https://pubmed.ncbi.nlm.nih.gov/26561784/

Doris Hexsel, Vivian Zague, Michael Schunck, Carolina Siega, Fernanda O Camozzato, Steffen Oesser, NCBI, "Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails", at https://pubmed.ncbi.nlm.nih.gov/28786550/https://pubmed.ncbi.nlm.nih.gov/28786550/

 

Disclaimer: 
This offer does not replace a medical diagnosis or treatment. For health-related questions, please consult a specialist. Before/after pictures show examples; individual results may vary.

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